New and Bioactive Secondary Metabolites from Ma-rine and Terrestrial Bacteria: Ramthacin A, B, C, and Polyene Macrolides from Genetically Modified Bacteria
von Ibrahim Al-Refa Mahmoud Hussien
Datum der mündl. Prüfung:2008-10-30
Erschienen:2009-01-09
Betreuer:Prof. Dr. Hartmut Laatsch
Gutachter:Prof. Dr. Axel Zeeck
Dateien
Name:al_refai.pdf
Size:3.51Mb
Format:PDF
Description:Dissertation
Zusammenfassung
Englisch
Natural products have provided the major sources of chemical diversity for phar-maceutical discoveries for many decades. For clinical application to treat human dis-eases in almost all therapeutic areas, many natural products and synthetically modi-fied natural products have been successfully used. In the search for novel and bioac-tive molecules for discovery of new drugs, marine-derived natural resources are be-coming an important research area.
Keywords: Ma-rine Bacteria Terrestrial Bacteria; Ramthacin A; B; C; Polyene Macrolides