dc.contributor.advisor | Fasshauer, Dirk Prof. Dr. | de |
dc.contributor.author | Iraheta, Raul Emilio | de |
dc.date.accessioned | 2013-01-04T18:37:44Z | de |
dc.date.accessioned | 2013-01-18T14:22:16Z | de |
dc.date.available | 2013-01-30T23:50:56Z | de |
dc.date.issued | 2013-01-04 | de |
dc.identifier.uri | http://hdl.handle.net/11858/00-1735-0000-000D-F0CC-3 | de |
dc.identifier.uri | http://dx.doi.org/10.53846/goediss-3160 | |
dc.format.mimetype | application/pdf | de |
dc.language.iso | eng | de |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/ | de |
dc.title | Sec1p/Munc18 (SM) proteins and their role in regulating secretion in Saccharomyces cerevisiae and Caenorhabditis elegans a comparative approach | de |
dc.type | doctoralThesis | de |
dc.title.translated | Sec1p/Munc18 (SM) proteine und deren Rolle in der Sekretionsregulierung in Saccharomyces cerevisiae und Caenorhabditis elegans -eine vergleichende Studie | de |
dc.contributor.referee | Fasshauer, Dirk Prof. Dr. | de |
dc.date.examination | 2012-11-20 | de |
dc.subject.dnb | 500 Naturwissenschaften | de |
dc.subject.gok | Biophysik (PPN619462817) | de |
dc.description.abstracteng | The members of the Sec1p/Munc18 (SM)
family of proteins are indispensible regulatory elements that act
at the post-docking step prior to fusion; they exert their function
mainly through their interaction to the Qa-SNAREs (Syntaxins).
Although studies have shown a high degree of structural homology,
different binding modes have been proposed. In the case of the
neuronal Munc18-1, an affinity towards a “close conformation | de |
dc.contributor.coReferee | Ficner, Ralf Prof. Dr. | de |
dc.contributor.thirdReferee | Wahl, Markus Prof. Dr. | de |
dc.subject.topic | Göttingen Graduate School for Neurosciences and Molecular Biosciences (GGNB) | de |
dc.subject.ger | ITC | de |
dc.subject.ger | Syntaxin | de |
dc.subject.ger | SNAREs | de |
dc.subject.ger | Membrane Fusion | de |
dc.subject.ger | Neuronal Secretion | de |
dc.subject.ger | Sec1/Munc18 | de |
dc.subject.ger | Biochemitry | de |
dc.subject.ger | Protein-Protein Interactions | de |
dc.subject.eng | ITC | de |
dc.subject.eng | Syntaxin | de |
dc.subject.eng | SNAREs | de |
dc.subject.eng | Membrane Fusion | de |
dc.subject.eng | Neuronal Secretion | de |
dc.subject.eng | Sec1/Munc18 | de |
dc.subject.eng | Biochemitry | de |
dc.subject.eng | Protein-Protein Interactions | de |
dc.subject.bk | Biologie | de |
dc.identifier.urn | urn:nbn:de:gbv:7-webdoc-3856-4 | de |
dc.identifier.purl | webdoc-3856 | de |
dc.affiliation.institute | Göttinger Graduiertenschule für Neurowissenschaften und Molekulare Biowissenschaften (GGNB) | de |
dc.identifier.ppn | 737345764 | de |