Human- und Zahnmedizin: Recent submissions
Now showing items 1-20 of 2862
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Prospektive Untersuchung des Schädelwachstums Frühgeborener von Geburt bis zum errechneten Geburtstermin
(2024-03-28)Using stereophotogrammetry for a longitudinal 3D analysis of the head growth of preterm born neonates from birth to term. -
Evaluation des therapeutischen Potentials von intravenös appliziertem Metallothionein-II im Schlaganfall Modell der Maus unter Thrombolyse
(2024-03-27)Stroke is the second leading cause of death worldwide. The only available drug therapy is thrombolysis using recombinant tissue-specific plasminogen activator (rtPA), which can only be used to a limited extent due to the ... -
Der Einfluss von Aβ4-42 auf die Kognition und die Anwendung von Suchstrategien im Morris Water Maze im Tg4-42-Mausmodell
(2024-03-25)The relevance of Alzheimer's dementia for our society is increasing. Soluble amyloid beta (Aβ) plays a particularly important role in the genesis of this disease. Aβ4-42 in particular, which is truncated before the fourth ... -
Rolle des G-Protein-gekoppelten Östrogenrezeptors 1 (GPER1) beim Zervixkarzinom
(2024-03-21)Cervical cancer is the fourth most common cancer in women and after the mamma carcinoma the second most common gynecological carcinoma. The G-Protein-coupled Estrogen Receptor 1 (GPER1) is an important ubiquitous receptor ... -
Epigenetische Grundlagen der (Kreuz)-Resistenz von Antiandrogenen neuer und neuster Generation
(2024-03-20)Prostate cancer grows androgene-dependent, because of which, antiandrogen therapy is used in advanced tumor stages. Most antiandrogens inhibit the androgen receptor directly, but Abiraterone inhibits androgen synthesis. ... -
Die prognostische Bedeutung von Vorhofflimmern bei Patienten mit akuter Lungenembolie
(2024-03-18)Background: Although prior studies indicate a high prevalence of atrial fibrillation (AF) in patients with pulmonary embolism (PE), the exact prevalence and prognostic impact are unknown. Methods: We aimed to investigate ... -
Individualisierung menschlicher Überreste in zwei historischen Schädelsammlungen der Universität Göttingen und ihr Beitrag zur bioanthropologischen Provenienzforschung
(2024-03-14)The University of Göttingen is in possession of two large collections of human remains: The Blumenbach Skull Collection and the Anthropological Collection. Human remains from Hawaii and Tanzania with a colonial context ... -
Korrelation der 5-Flucytosin-Resistenz in Candida albicans mit Markerpeak im MALDI-Massenspektrum durch neue Extraktionsmethode
(2024-03-06)Candida albicans is a facultative pathogenic fungus that occurs worldwide and is found in the gastrointestinal tract of the majority of people. In immunocompromised patients, however, it can lead to severe systemic infections. ... -
Auswirkung von verschiedenen Gefäßklemmen auf die Kollagenmatrix der ovinen biosynthetischen Gefäßprothese
(2024-03-04)Background: Ovine biosynthetic prostheses have established themselves in the field of vascular surgery; they can be used effectively both for septic vascular surgery – in cases where there are no autogenous bypass materials ... -
Einfluss genetischer Varianten der negativ-kostimulierenden T-Zell-Inhibitoren TIM-3 und LAG-3 auf das Outcome von Patienten mit Sepsis
(2024-03-04)Background: Each year, millions of people die from sepsis or its consequences. Sepsis is defined as a life-threatening condition based on a dysregulated immune response to an infection. Thus, investigating the complex ... -
Einfluss der klinischen und interventionellen Parameter im Rahmen der mpMRT/TRUS Fusionsbiopsie der Prostata auf die Detektionsrate des Prostatakarzinoms
(2024-03-01)Prostate cancer is one of the most common cancers in men worldwide. In this context, this study investigates clinical and interventional parameters that may influence the detection rate of prostate cancer in the context ... -
Kardiovaskuläre Einflussfaktoren auf die gesundheitsbezogene Lebensqualität von onkologischen Patienten
(2024-02-29)Aims Five percent of the German population is living with the diagnosis of a malignant disease, which transforms – due to higher survival rates – to a chronic disease. Maintaining quality of life (QoL) has become increasingly ... -
Evaluation des Göttinger Kooperationsprojekts FIDEM (Frühe Informationen und Hilfen bei Demenz): Projekt-Etablierung und Erfahrungen von ärztlichen sowie nicht-ärztlichen Beteiligten
(2024-02-21)Early information and support in dementia (FIDEM) is a cooperation model that focuses on networking between general practitioners and non-medical cooperation partners (e.g. occupational therapists, care counselling, other ... -
Weitwinkel-Angiographie-Bildgebung zur Detektion von Ischämien bei Retinalen Venenverschlüssen
(2024-02-21)Retinal vein occlusions (RVO) are a relatively common and clinically relevant ophthalmological condition with numerous potential complications. Since diagnosis using fluorescein angiography (FAG) imaging, particularly the ... -
Einfluss der Zeit zwischen Diagnose und Therapie des Prostatakarzinoms mittels radikaler Prostatektomie auf klinische und onkologische Parameter
(2024-02-16)Prostate cancer is currently the most common cancer diagnosis among men in Germany and ranks among the top fatal diseases. Particularly in times of pandemic, the influence of the time interval between histological confirmation ... -
Short- and long-term quality of life in patients after surgically treated Spondylodiscitis
(2024-02-13)Background Spondylodiscitis affects a fragile patient population frequently fraught with severe comorbidities. Data on long-term outcomes, especially for patients undergoing surgery, are scarce. The aim of this study was ... -
Auswirkungen einer Variation im TREM-1-Gen auf die Mortalität bei septischen Patienten
(2024-02-12)Sepsis is a life-threatening organ dysfunction caused by a disturbed immune response of the organism to an infectious agent. Sepsis is one of the most common causes of death in intensive care units. Due to its epidemiology ... -
Chirurgische Behandlung der isolierten Aortenisthmusstenose: Risiken und Komplikationen im Langzeitverlauf
(2024-02-09)Aortic coarctation is the fifth most common congenital heart defect in Germany. Pathophysiologically, it is a narrowing at the distal end of the aortic arch, which results in reduced perfusion in the lower half of the body. ... -
MET-Alterationen als therapeutisches Target bei metastasierten kolorektalen Karzinomen
(2024-02-09)Introduction: An enhanced understanding of the molecular pathways driving oncogenesis has yielded an increasing number of potential therapeutic targets. MET amplification has been shown to be involved in angiogenesis, ... -
Match-paired study to assess influence of Kinematic versus Mechanical Alignment in Total Knee Replacement
(2024-02-09)Introduction: Match-paired study compares the early clinical and radiological outcomes after 6 weeks and 1-year between kinematic alignment total knee arthroplasty (KA TKA) and mechanical alignment total knee arthroplasty ...