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Analyse biologischer Signaltransduktionsnetzwerke auf der Grundlage von Genexpressionsdaten

Analysis of Biological Signal Transduction Networks based on Gene Expression Data

by Jost Degenhardt
Doctoral thesis
Date of Examination:2010-08-10
Date of issue:2010-08-09
Advisor:Prof. Dr. Edgar Wingender
Referee:Prof. Dr. Tim Beißbarth
crossref-logoPersistent Address: http://dx.doi.org/10.53846/goediss-835

 

 

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Abstract

English

A method that combines gene expression data with biological expert knowledge on molecular interaction networks, as described by the TRANSPATH database on signal transduction, to predict additional and not necessarily differentially expressed genes or gene products which might participate in processes specific for either of the examined tissues or conditions.
Keywords: Bioinformatics; Biological Networks

Other Languages

Eine Methode, die Genexpressionsdaten mit biologischem Expertenwissen über Signaltransduktionsnetzwerke kombiniert, um zusätzliche, nicht differentiell exprimierte, Gene oder Genprodukte zu identifizieren, die eine spezifische Rolle für die untersuchten Gewebe bzw. Zustände spielen könnten.
Schlagwörter: Bioinformatik; Biologische Netzwerke
 

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