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Transport von Glutathion über natriumabhängige Transporter der basolateralen Membran proximaler Tubuluszellen

Transport of glutathione across the basolateral membrane of proximal tubule by sodium-dependent transporters

by Lena Schorbach
Doctoral thesis
Date of Examination:2011-04-12
Date of issue:2011-04-04
Advisor:Prof. Dr. Gerhard Burckhardt
Referee:Prof. Dr. Martin Oppermann
Referee:PD Dr. Abdul Rahman Asif
crossref-logoPersistent Address: http://dx.doi.org/10.53846/goediss-971

 

 

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Abstract

English

This dissertation deals with the renal basolateral transport of glutathione (GSH). It is known, that this transport is sodium-dependent. Now, the hypothesis is to be proved, if one or both known sodium-dependent transporters which are located in the basolateral plasma membrane might be involved in this transport of GSH.
Keywords: glutathione; GSH; sodium-dependent

Other Languages

Die Arbeit befasst sich mit der Frage, welche Transportsysteme der basolateralen Membran proximaler Tubuluszellen am Transport von Glutathion (GSH) beteiligt sind. Es ist bekannt, dass dieser Transport natriumabhängig ist. Nun soll die Hypothese überprüft werden, ob einer oder beide der bisher bekannten, natriumabhängigen Carboxylat-Transporter (hNaDC3, hNaCT) für diesen Transport von GSH verantwortlich sein könnten.
Schlagwörter: Glutathion; GSH; hNaDC3; hNaCT; Dikarboxylate
 

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