Requirement of HSP70s in the cytosol to vacuole transport of aminopeptidase 1 in Saccharomyces cerevisiae

Satyanarayana, Chitkala

dc.contributor.advisor	Figura, Kurt von Prof. Dr. Dr. h.c.	de
dc.contributor.author	Satyanarayana, Chitkala	de
dc.date.accessioned	2012-05-16T12:13:00Z	de
dc.date.available	2013-01-30T23:50:31Z	de
dc.date.issued	2000-10-27	de
dc.identifier.uri	http://hdl.handle.net/11858/00-1735-0000-0006-B6EC-2	de
dc.identifier.uri	http://dx.doi.org/10.53846/goediss-1424
dc.format.mimetype	ContentType:application/pdf Size:1.222	de
dc.language.iso	ger	de
dc.rights.uri	http://webdoc.sub.gwdg.de/diss/copyrdiss.htm	de
dc.title	Requirement of HSP70s in the cytosol to vacuole transport of aminopeptidase 1 in Saccharomyces cerevisiae	de
dc.type	doctoralThesis	de
dc.contributor.referee	Figura, Kurt von Prof. Dr. Dr. h.c.	de
dc.date.examination	2000-11-01	de
dc.subject.dnb	500 Naturwissenschaften allgemein	de
dc.description.abstracteng	In Saccharomyces cerevisiae, aminopeptidase 1 (Ape1p) is a vacuolar resident protein which is transported to the vacuole by a non classical pathway. On synthesis in the cytoplasm the protein assembles into a homododecamer and is transported directly into the vacuole. It does not take the classical secretory pathway which is taken by most of the vacuolar resident proteins. A translocation as well as a vesicle mediated process have been suggested to describe the cytosol to vacuole targeting of Ape1p. Heat shock proteins of the 70 kDa family are known to assist in the transport of proteins into various organelles like the mitochondria, endoplasmic reticulum and nucleus. In this project we determined that the cytosolic members of the heat shock proteins of the 70 kDa family (HSP70s) assist in the transport of aminopeptidase 1 to the vacuole.	de
dc.contributor.coReferee	Robinson, David Gordon Prof. Dr.	de
dc.subject.topic	Mathematics and Computer Science	de
dc.subject.eng	Cytosol to vacuole transport	de
dc.subject.eng	aminopeptidase 1	de
dc.subject.eng	heat shock proteins	de
dc.subject.bk	30 Naturwissenschaften allgemein	de
dc.identifier.urn	urn:nbn:de:gbv:7-webdoc-932-7	de
dc.identifier.purl	webdoc-932	de
dc.affiliation.institute	Medizinische Fakultät	de
dc.subject.gokfull	RA Naturwissenschaften allgemein	de
dc.identifier.ppn	327597097

Dateien

Name:csataya.pdf

Größe:1.192Mb

Format:PDF

Beschreibung:Dissertation

Öffnen

Name:: csataya.pdf
Größe:: 1.192Mb
Format:: PDF
Beschreibung:: Dissertation

Öffnen

Das Dokument erscheint in:

Human- und Zahnmedizin [2872]

Zur Kurzanzeige