Dokumente Molekulare Medizin nach Gutachter "Hahn, Heidi Prof. Dr."

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    • The role of Pygo2 during intestinal tumor initiation and progression in vivo 

      Talla, Suranand Babu (2016-05-12)
      Canonical Wnt signaling pathway is an essential regulator of embryonic development as well homeostasis of adult tissues and stem cell proliferation. Familial or sporadic mutations of genes of Wnt signaling components are ...

    • The role of SNAP29 during epidermal differentiation 

      Seebode, Christina (2015-12-11)
      The human CEDNIK syndrome is caused by loss-of-function mutations in the SNAP29 gene, encoding a member of the SNARE family of proteins. So far, no Snap29-deficient mammalian animal models have been described for this rare ...

    • Uncovering triggers of colonization in brain metastasis 

      Blazquez, Raquel (2017-04-26)
      Brain metastases (BM) are frequent in cancer patients and are associated with poor prognosis. The incidence of BM is increasing mainly due to an improved control of primary tumors and an increased median survival of the ...