Browsing Molekulare Medizin by Author "Geyer, Natalie"
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Targeting the Hedgehog and PI3K/AKT/mTOR signaling pathways in rhabdomyosarcoma
Geyer, Natalie (2018-12-18)Rhabdomyosarcoma (RMS) is the most common pediatric soft tissue sarcoma with poor prognosis. RMS, and especially the embryonal subtype (ERMS), show activation of Hedgehog (HH) signaling. In patients with Gorlin syndrome, ...