Browsing Molekulare Medizin by Author "Isermann, Tamara"
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Modulation of HSF1 activity by p53 and its impact in cancer therapies
Isermann, Tamara (2023-07-13)The tumor suppressor p53 (TP53) is mutated in ~70 % of colorectal cancer (CRC) cases. Of these cases, approximately 80 % undergo subsequent p53 loss-of-heterozygosity (p53LOH), losing the remaining wildtype p53 (WTp53) ...