Browsing Molekulare Medizin by Author "Johnston, Alexander"

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Examining the interplay between oxidative and β-adrenergic regulation of PKARIα and its impact on the mitochondrial fission protein DRP1

Johnston, Alexander (2017-07-03)

PKA is activated by β-adrenergic signaling induced elevation in intracellular cAMP and sequestered into proximity with its substrates by scaffold A-kinase anchoring proteins (AKAPs). PKARIα is a unique isoform of PKA as ...