Browsing Molekulare Medizin by Advisor & Referee "Brose, Nils Prof. Dr."
Now showing items 1-3 of 3
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Amyloid-β and phospho-Tau biomarkers immunoassay development and optimization to support the blood-based early and differential diagnosis of Alzheimer’s disease
(2025-10-13)The recent emergence of anti-amyloid treatments for early symptomatic Alzheimer’s disease (AD) require biomarker confirmation of amyloid pathology, increasing the need for biomarker testing. In the last few years, there ... -
Understanding Early Events of B Cell Antigen Receptor Activation: Effects of Antigen and Receptor Valency
(2025-03-07)Abstract Each B cell is equipped with B cell antigen receptors (BCRs) of a unique specificity. These BCRs are crucial in many events including B cell development, activation and differentiation. There is still an ongoing ... -
Alpha-synuclein-associated alterations at the synapse in models of Parkinson’s disease
(2023-08-16)Parkinson’s disease (PD) is one of the most common neurodegenerative disorders that is characterized by the typical motor features, and also by a multiplicity of non-motor symptoms. The main pathological hallmarks of PD ...