Browsing Molekulare Medizin by Advisor & Referee "Goya-Maldonado, Roberto PD Dr."
Now showing items 1-3 of 3
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Cellular prion protein in Alzheimer’s disease: Molecular insights and behavior implications
(2024-01-11)Alzheimer’s disease (AD) poses a substantial and increasing challenge, particularly due to our aging population, and its underlaying pathophysiology remains a topic of ongoing debate. Cellular prion protein (PrPC) has ... -
Alpha-synuclein-associated alterations at the synapse in models of Parkinson’s disease
(2023-08-16)Parkinson’s disease (PD) is one of the most common neurodegenerative disorders that is characterized by the typical motor features, and also by a multiplicity of non-motor symptoms. The main pathological hallmarks of PD ... -
Optimization of the RT-QuIC in prion disease diagnostic
(2023-01-11)In the present work, we were interested in applying different recombinant prion proteins (rec PrP) as substrates in the real-time quaking-induced conversion (RT-QuIC) assay to improve the diagnostic accuracy in different ...