Browsing Molekulare Medizin by Advisor & Referee "Pardo, Luis A. Dr."
Now showing items 1-3 of 3
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Novel therapeutic approaches for PDAC targeting potassium channels
(2023-12-07)Combining targeted and conventional therapies holds promise for the handling of challenging cancers. In this study, we propose the combination of the TNF-related apoptosis-inducing ligand (TRAIL) with Kv10.1-targeting ... -
Therapeutic strategies targeting Kv10.1 in PDAC
(2017-01-19)This study was conducted to explore the suitability of the voltage gated potassium channel Kv10.1 as a novel therapeutic target in pancreatic ductal adenocarcinoma (PDAC). PDAC, which is characterized by marked invasiveness, ... -
The Kv10.1 voltage gated potassium ion channel modulates the cell adhesion and cell migration hallmarks of cancer
(2015-06-23)A characteristic of the Kv10.1 voltage-gated potassium ion channel is its overexpression in a number of cancerous tissues and cancer cell lines, even though it should normally be restricted to the adult brain and myoblasts. ...