Browsing Molekulare Medizin by Advisor & Referee "Urlaub, Henning Prof. Dr."
Now showing items 1-6 of 6
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Effects of acute and long-term tachypacing on atrial engineered human myocardium
(2023-04-27)Atrial fibrillation is the most common supraventricular arrhythmia and is associated with molecular remodelling that promotes the maintenance and worsening of the disease. Although extensive research has been performed to ... -
Off the beaten path - An unbiased inventory of signal response elements in B cell receptor signaling
(2021-04-06)Signaling through the B cell antigen receptor (BCR) is indispensable for B lymphocyte maturation, activation and differentiation. Antigenic signal transduction thus constitutes a centerpiece of adaptive immunity and its ... -
Functional and diagnostic relevance of FGFR1-dependent signaling pathways in squamous cell lung cancer
(2020-09-22)Lung cancer continuous to be the leading cause of cancer-related death worldwide. A relatively new and effective approach of treating lung cancer is achieved through targeting specific molecular alterations in lung cancer ... -
A cell-type and compartment specific analysis of glutathione and hydrogen peroxide
(2019-07-04)Reactive oxygen species (ROS) have been recognized to play important roles as messenger molecules. They are involved in the etiology and progression of cardiovascular diseases such as myocardial infarction, cardiac hypertrophy ... -
WNT signalling affects cell migration, invasion and the lymphoma-endothelial interplay in Hodgkin Lymphoma
(2016-06-23)Classical Hodgkin Lymphoma (cHL) comprises a unique cancer where the microenvironment accounts for 99 % of the whole tumour mass. In cHL dissemination involves functionally neighbouring lymph nodes but the underlying ... -
CIN85 in proximal and distant B cell antigen receptor signaling
(2016-03-15)B cell antigen receptor (BCR) signaling is pivotal in B cell development and initiation of humoral immune responses. In this process, numerous proteins are involved that interact with each other and build up a sophisticated ...