Browsing Molekulare Medizin by Advisor & Referee "Wegwitz, Florian Dr."
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The role of histone 2B monoubiquitination (H2Bub1) in HER2-driven mammary carcinoma
(2021-03-25)Breast cancer (BC) is the most frequent tumor entity in women worldwide with a high chance of therapeutic response in early- and non-metastatic disease stage. Despite the advent of HER2-specific targeted therapies, a ... -
Unravelling epigenetic mechanisms of CAF-chemotherapy resistance in mammary carcinoma
(2020-01-29)Triple negative breast cancer (TNBC) is one of the most challenging cancers to treat as, despite the initial response to chemotherapy, relapse occurs frequently. In this project, we focused on the mechanisms that allow ...