Browsing Molekulare Medizin by Advisor & Referee "Wirths, Oliver Prof. Dr."
Now showing items 1-3 of 3
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Long-term Replacement of Endogenous Microglia in Mice
(2024-12-19)Microglia are the resident immune cells of the central nervous system (CNS). They play pivotal roles in the development and homeostasis of the CNS and have been implicated in neurodegenerative disorders, such as Alzheimer´s ... -
Role of the cellular prion protein in the cellular internalization and the Tau-mediated toxicity
(2024-11-15)Tauopathies represent a group of neurodegenerative disorders characterized by the accumulation of Tau within the brain, leading to neuronal dysfunction and death. These diseases are classified into 3R tauopathies, 4R ... -
Cellular prion protein in Alzheimer’s disease: Molecular insights and behavior implications
(2024-01-11)Alzheimer’s disease (AD) poses a substantial and increasing challenge, particularly due to our aging population, and its underlaying pathophysiology remains a topic of ongoing debate. Cellular prion protein (PrPC) has ...