Blättern Molekulare Medizin nach "Meyer, Thomas Prof. Dr." Betreuer
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Cellular responses mediated by the transcription factor STAT1 in murine inflammatory diseases
(2017-01-12)The intracellular transduction of interferon signals from the plasma membrane to the nucleus is mediated by signal transducer and activator of transcription 1 (STAT1) which acts in tetrameric form as a transcription factor ... -
The importance of homotypic interactions of unphosphorylated STAT proteins in cytokine-induced signal transduction
(2021-03-12)Several cytokines mediate cellular responses via the family of transcription factors called signal transducers and activators of transcription (STAT). Though phosphorylated STATs (P-STAT) form the active and extensively ... -
The role of STAT1-cooperative DNA binding in myocardial infarction
(2019-08-09)Myocardial infarction (MI), defined as heart damage due to prolonged ischemia, accounts for significant mortality and morbidity and has a substantial financial burden worldwide. While major advancements have been achieved ...