Dokumente Molekulare Medizin nach Gutachter "Günesdogan, Ufuk Dr."
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Centrosome integrity as a determinant of replication stress
(2020-01-29)The centrosome functions as a microtubule-nucleating organelle for the mitotic spindle. Like the whole genome, centrosomes require accurate replication once per cell cycle. Here we show that the impairment of centrosome ... -
Interplay of ARID1A and EGFR signaling in controlling acinar cell reprogramming in the pancreas
(2021-03-18)Based on a high degree of cellular plasticity and triggered by external (e.g. inflammation) or internal (e.g. oncogenic pressure) signals, pancreatic acinar cells can undergo reprogramming processes resulting in acinar-to-ductal ...