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Pluripotency of multipotent adult germ-line stem cells: analysis of apoptotic and epigenetic features

dc.contributor.advisorEngel, Wolfgang Prof. Dr. Dr.de
dc.contributor.authorKhromov, Tatjanade
dc.date.accessioned2013-01-14T15:06:53Zde
dc.date.available2013-01-30T23:50:52Zde
dc.date.issued2012-05-10de
dc.identifier.urihttp://hdl.handle.net/11858/00-1735-0000-000D-EF56-Ede
dc.identifier.urihttp://dx.doi.org/10.53846/goediss-1458
dc.format.mimetypeapplication/pdfde
dc.language.isoengde
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/de
dc.titlePluripotency of multipotent adult germ-line stem cells: analysis of apoptotic and epigenetic featuresde
dc.typedoctoralThesisde
dc.title.translatedPluripotenz der multipotenten adulten Keimstammzellen: Analyse der apoptotischer und epigenetischer Merkmalede
dc.contributor.refereeEngel, Wolfgang Prof. Dr.de
dc.date.examination2011-11-29de
dc.subject.dnb500 Naturwissenschaftende
dc.subject.gokMED 301de
dc.description.abstractengPluripotency is the potential of cells to proliferate incessantly (self-renewal) and to develop into all cell types of the three germ layers as well as to the germ line. Recently established multipotent adult Germ-line Stem Cell (maGSC) lines are pluripotent cells derived from the unipotent Spermatogonial Stem Cells (SSCs) which acquire Embryonic Stem Cells (ESCs) properties in vitro. Since pluripotent maGSCs can have therapeutic potential in regenerative medicine by replacing the ethical problematic ESCs, several groups have studied the similarity of these cells to the “gold standard of pluripotencyde
dc.contributor.coRefereeHoyer-Fender, Sigrid Prof. Dr.de
dc.subject.topicBiology (incl. Psychology)de
dc.subject.gerStammzellende
dc.subject.gerKeimzellende
dc.subject.gerApoptosende
dc.subject.gerEpigenetikde
dc.subject.gerES Zellende
dc.subject.germaGS Zellende
dc.subject.engStem cellsde
dc.subject.engGerm cellsde
dc.subject.engES cellsde
dc.subject.engmaGSCde
dc.subject.engApoptosisde
dc.subject.engEpigenticsde
dc.subject.bk42.00de
dc.subject.bk42.13de
dc.subject.bk42.15de
dc.subject.bk42.20de
dc.subject.bk42.23de
dc.identifier.urnurn:nbn:de:gbv:7-webdoc-3496-9de
dc.identifier.purlwebdoc-3496de
dc.affiliation.instituteBiologische Fakultätde
dc.identifier.ppn720430321de


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