A great variability of remyelinisation is
frequently found in demyelinated plaques of patients with multiple
sclerosis (MS). Regarding this variability recent studies have
found a correlation between the Histone deacetylase 1
(HDAC1)-expression and the level of remyelinisation in mice. In
this study we concentrated on the question whether this coherence
also could be seen in patients with MS. Beforehand, we developed a
classification for stages of remyelinating lesions by means of
differential expression of various myelin proteins in
oligodendrocytes. It showed that 2
