Epigenetische Kontrolle der Remyelinisierung bei Multipler Sklerose

Herget, Anna Theresia

dc.contributor.advisor	Stadelmann-Nessler, Christine Prof. Dr.	de
dc.contributor.author	Herget, Anna Theresia	de
dc.date.accessioned	2013-01-14T15:25:50Z	de
dc.date.available	2013-01-30T23:51:06Z	de
dc.date.issued	2012-06-15	de
dc.identifier.uri	http://hdl.handle.net/11858/00-1735-0000-000D-EFCD-6	de
dc.identifier.uri	http://dx.doi.org/10.53846/goediss-1550
dc.format.mimetype	application/pdf	de
dc.language.iso	ger	de
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/	de
dc.title	Epigenetische Kontrolle der Remyelinisierung bei Multipler Sklerose	de
dc.type	doctoralThesis	de
dc.title.translated	Epigenetic control of remyelinisation in multiple sclerosis	de
dc.contributor.referee	Stadelmann-Nessler, Christine Prof. Dr.	de
dc.date.examination	2012-06-27	de
dc.subject.dnb	610 Medizin, Gesundheit	de
dc.subject.gok	MED 391	de
dc.description.abstracteng	A great variability of remyelinisation is frequently found in demyelinated plaques of patients with multiple sclerosis (MS). Regarding this variability recent studies have found a correlation between the Histone deacetylase 1 (HDAC1)-expression and the level of remyelinisation in mice. In this study we concentrated on the question whether this coherence also could be seen in patients with MS. Beforehand, we developed a classification for stages of remyelinating lesions by means of differential expression of various myelin proteins in oligodendrocytes. It showed that 2	de
dc.contributor.coReferee	Reuss, Bernhard Prof. Dr.	de
dc.subject.topic	Medicine	de
dc.subject.ger	Multiple Sklerose	de
dc.subject.ger	HDAC1	de
dc.subject.ger	Remyelinisierung	de
dc.subject.ger	Remyelinisierungsstadien	de
dc.subject.ger	NogoA	de
dc.subject.ger	CNP	de
dc.subject.ger	MOG	de
dc.subject.ger	MAG	de
dc.subject.ger	MBP	de
dc.subject.eng	multiple sclerosis	de
dc.subject.eng	HDAC1	de
dc.subject.eng	remyelinisation	de
dc.subject.eng	stages of remyelinisation	de
dc.subject.eng	NogoA	de
dc.subject.eng	CNP	de
dc.subject.eng	MOG	de
dc.subject.eng	MAG	de
dc.subject.eng	MBP	de
dc.subject.bk	44.46	de
dc.subject.bk	44.78	de
dc.identifier.urn	urn:nbn:de:gbv:7-webdoc-3562-1	de
dc.identifier.purl	webdoc-3562	de
dc.affiliation.institute	Medizinische Fakultät	de
dc.identifier.ppn	728998181	de

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Human- und Zahnmedizin [2872]

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