dc.contributor.advisor | Stadelmann-Nessler, Christine Prof. Dr. | de |
dc.contributor.author | Herget, Anna Theresia | de |
dc.date.accessioned | 2013-01-14T15:25:50Z | de |
dc.date.available | 2013-01-30T23:51:06Z | de |
dc.date.issued | 2012-06-15 | de |
dc.identifier.uri | http://hdl.handle.net/11858/00-1735-0000-000D-EFCD-6 | de |
dc.identifier.uri | http://dx.doi.org/10.53846/goediss-1550 | |
dc.format.mimetype | application/pdf | de |
dc.language.iso | ger | de |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/ | de |
dc.title | Epigenetische Kontrolle der Remyelinisierung bei Multipler Sklerose | de |
dc.type | doctoralThesis | de |
dc.title.translated | Epigenetic control of remyelinisation in multiple sclerosis | de |
dc.contributor.referee | Stadelmann-Nessler, Christine Prof. Dr. | de |
dc.date.examination | 2012-06-27 | de |
dc.subject.dnb | 610 Medizin, Gesundheit | de |
dc.subject.gok | MED 391 | de |
dc.description.abstracteng | A great variability of remyelinisation is
frequently found in demyelinated plaques of patients with multiple
sclerosis (MS). Regarding this variability recent studies have
found a correlation between the Histone deacetylase 1
(HDAC1)-expression and the level of remyelinisation in mice. In
this study we concentrated on the question whether this coherence
also could be seen in patients with MS. Beforehand, we developed a
classification for stages of remyelinating lesions by means of
differential expression of various myelin proteins in
oligodendrocytes. It showed that 2 | de |
dc.contributor.coReferee | Reuss, Bernhard Prof. Dr. | de |
dc.subject.topic | Medicine | de |
dc.subject.ger | Multiple Sklerose | de |
dc.subject.ger | HDAC1 | de |
dc.subject.ger | Remyelinisierung | de |
dc.subject.ger | Remyelinisierungsstadien | de |
dc.subject.ger | NogoA | de |
dc.subject.ger | CNP | de |
dc.subject.ger | MOG | de |
dc.subject.ger | MAG | de |
dc.subject.ger | MBP | de |
dc.subject.eng | multiple sclerosis | de |
dc.subject.eng | HDAC1 | de |
dc.subject.eng | remyelinisation | de |
dc.subject.eng | stages of remyelinisation | de |
dc.subject.eng | NogoA | de |
dc.subject.eng | CNP | de |
dc.subject.eng | MOG | de |
dc.subject.eng | MAG | de |
dc.subject.eng | MBP | de |
dc.subject.bk | 44.46 | de |
dc.subject.bk | 44.78 | de |
dc.identifier.urn | urn:nbn:de:gbv:7-webdoc-3562-1 | de |
dc.identifier.purl | webdoc-3562 | de |
dc.affiliation.institute | Medizinische Fakultät | de |
dc.identifier.ppn | 728998181 | de |