Untersuchungen zur Regulation der Zelladhäsion durch PHD2 in Tumorzellen
Investigation on the role of PHD2 in the regulation of cell adhesion in tumor cells
von Moritz Thomas Schnelle
Datum der mündl. Prüfung:2012-08-14
Erschienen:2012-07-24
Betreuer:Prof. Dr. Dörthe Katschinski
Gutachter:Prof. Dr. Dörthe Katschinski
Gutachter:Prof. Dr. Matthias Dobbelstein
Gutachter:Prof. Dr. Martin Oppermann
Dateien
Name:schnelle.pdf
Size:1.05Mb
Format:PDF
Zusammenfassung
Englisch
The hypoxia-inducible factor 1 (HIF-1) is a transcription factor, which is stabilized under hypoxic conditions. It consists of the HIF-1β- as well as of one of three known HIF-α-subunits. One of its
Keywords: hypoxia; PHD2; HIF-1α; cell adhesion; metastasation; SPARC; SPP1; cofilin
Schlagwörter: Hypoxie; PHD2; HIF-1α; Zelladhäsion; Metastasierung; SPARC; SPP1; Cofilin