Der Einfluss von Melatonin auf den nephroprotektiven Effekt von Endothelprogenitorzellen im Mausmodell

Hildebrandt, Axel

dc.contributor.advisor	Patschan, Daniel PD Dr.	de
dc.contributor.author	Hildebrandt, Axel	de
dc.date.accessioned	2013-01-14T15:30:19Z	de
dc.date.available	2013-01-30T23:50:51Z	de
dc.date.issued	2012-08-24	de
dc.identifier.uri	http://hdl.handle.net/11858/00-1735-0000-000D-F000-9	de
dc.identifier.uri	http://dx.doi.org/10.53846/goediss-1601
dc.format.mimetype	application/pdf	de
dc.language.iso	ger	de
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/	de
dc.title	Der Einfluss von Melatonin auf den nephroprotektiven Effekt von Endothelprogenitorzellen im Mausmodell	de
dc.type	doctoralThesis	de
dc.title.translated	The influence of melatonin to the renoprotective effect of endothelial progenitor cells in mouse models	de
dc.contributor.referee	Patschan, Daniel PD Dr.	de
dc.date.examination	2012-08-15	de
dc.subject.dnb	610 Medizin, Gesundheit	de
dc.subject.gok	MED 310 Physiologie	de
dc.description.abstracteng	As part of the study was to investigate whether the nephro-protective effect of endothelial progenitor cells can be enhanced by pretreatment of cells with melatonin. In animal experiments, the left kidney of experimental mice was exposed to a renal ischemia of 40 minutes. After ischemia the appropriate solution (corresponding to the respective group) was injected into the vessel of the contralateral kidney which was removed afterwards. Therefore the complete renal function has been taken over from the pre-damaged ischemic kidney. A statement on the renal function was made on the basis of creatinine in blood after two days. The renal damage was assessed microscopically in paraffin sections and evaluated semi-quantitatively. There are four groups studied, and the creatinine was compared to a control group. The animals of the first group was injected 50	de
dc.contributor.coReferee	Schäfer, Katrin Prof. Dr.	de
dc.contributor.thirdReferee	Mausberg, Rainer Prof. Dr.	de
dc.subject.topic	Medicine	de
dc.subject.ger	Akutes Nierenversagen	de
dc.subject.ger	Endotheliale Vorläuferzellen	de
dc.subject.ger	Endothel Progenitor Zellen	de
dc.subject.ger	Melatonin	de
dc.subject.eng	Acute ischemic renal failure	de
dc.subject.eng	Endothelial progenitor cells	de
dc.subject.eng	Melatonin	de
dc.subject.bk	44.03 Methoden und Techniken der Medizin	de
dc.identifier.urn	urn:nbn:de:gbv:7-webdoc-3668-0	de
dc.identifier.purl	webdoc-3668	de
dc.affiliation.institute	Medizinische Fakultät	de
dc.identifier.ppn	73059131X	de

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Human- und Zahnmedizin [2871]

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