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Solid-state NMR characterization of Alzheimer-like tau amyloid fibrils

Charakterisierung Alzheimer-verwandter Tau Amyloidfibrillen mittels Festkörper-NMR

by Venita Daebel
Doctoral thesis
Date of Examination:2012-08-27
Date of issue:2012-09-27
Advisor:Dr. Adam Lange
Referee:Prof. Dr. Christian Griesinger
Referee:Prof. Dr. Ulf Diederichsen
Referee:Dr. Adam Lange
crossref-logoPersistent Address: http://dx.doi.org/10.53846/goediss-2190

 

 

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Abstract

English

One of the hallmarks of Alzheimer's disease (AD) is the self-assembly of the microtubule-associated protein tau into fibers termed “paired helical filaments
Keywords: Alzheimer's Disease; Tau; Amyloid Fibril; Solid-State NMR; PHF
Schlagwörter: Morbus Alzheimer; Tau; Amyloid; Festkörper-NMR; PHF
 

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