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Sec1p/Munc18 (SM) proteins and their role in regulating secretion in Saccharomyces cerevisiae and Caenorhabditis elegans a comparative approach

dc.contributor.advisorFasshauer, Dirk Prof. Dr.de
dc.contributor.authorIraheta, Raul Emiliode
dc.date.accessioned2013-01-04T18:37:44Zde
dc.date.accessioned2013-01-18T14:22:16Zde
dc.date.available2013-01-30T23:50:56Zde
dc.date.issued2013-01-04de
dc.identifier.urihttp://hdl.handle.net/11858/00-1735-0000-000D-F0CC-3de
dc.identifier.urihttp://dx.doi.org/10.53846/goediss-3160
dc.format.mimetypeapplication/pdfde
dc.language.isoengde
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/de
dc.titleSec1p/Munc18 (SM) proteins and their role in regulating secretion in Saccharomyces cerevisiae and Caenorhabditis elegans a comparative approachde
dc.typedoctoralThesisde
dc.title.translatedSec1p/Munc18 (SM) proteine und deren Rolle in der Sekretionsregulierung in Saccharomyces cerevisiae und Caenorhabditis elegans -eine vergleichende Studiede
dc.contributor.refereeFasshauer, Dirk Prof. Dr.de
dc.date.examination2012-11-20de
dc.subject.dnb500 Naturwissenschaftende
dc.subject.gokBiophysik (PPN619462817)de
dc.description.abstractengThe members of the Sec1p/Munc18 (SM) family of proteins are indispensible regulatory elements that act at the post-docking step prior to fusion; they exert their function mainly through their interaction to the Qa-SNAREs (Syntaxins). Although studies have shown a high degree of structural homology, different binding modes have been proposed. In the case of the neuronal Munc18-1, an affinity towards a “close conformationde
dc.contributor.coRefereeFicner, Ralf Prof. Dr.de
dc.contributor.thirdRefereeWahl, Markus Prof. Dr.de
dc.subject.topicGöttingen Graduate School for Neurosciences and Molecular Biosciences (GGNB)de
dc.subject.gerITCde
dc.subject.gerSyntaxinde
dc.subject.gerSNAREsde
dc.subject.gerMembrane Fusionde
dc.subject.gerNeuronal Secretionde
dc.subject.gerSec1/Munc18de
dc.subject.gerBiochemitryde
dc.subject.gerProtein-Protein Interactionsde
dc.subject.engITCde
dc.subject.engSyntaxinde
dc.subject.engSNAREsde
dc.subject.engMembrane Fusionde
dc.subject.engNeuronal Secretionde
dc.subject.engSec1/Munc18de
dc.subject.engBiochemitryde
dc.subject.engProtein-Protein Interactionsde
dc.subject.bkBiologiede
dc.identifier.urnurn:nbn:de:gbv:7-webdoc-3856-4de
dc.identifier.purlwebdoc-3856de
dc.affiliation.instituteGöttinger Graduiertenschule für Neurowissenschaften und Molekulare Biowissenschaften (GGNB)de
dc.identifier.ppn737345764de


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