Morphometrischer Vergleich der Gewebeveränderung bei Weichgewebedissektion mit dem Ultraschallskalpell und monopolarer Elektrokoagulation

Morphometrischer Vergleich der Gewebeveränderung bei Weichgewebedissektion mit dem Ultraschallskalpell und monopolarer Elektrokoagulation

Morphometric tissue alteration in soft tissue dissection caused by ultrasonic scalpel compared to monopolar electrocautery

Meis, Johanna

Dissertation

Angenommen am: 2014-02-11

Erschienen: 2014-02-04

Betreuer: Langer, Claus Prof. Dr.

Gutachter: Wilting, Jörg Prof. Dr.

Gutachter: Kretschmer, Lutz Prof. Dr.

Zum Verlinken/Zitieren: http://hdl.handle.net/11858/00-1735-0000-0022-5E0F-2

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Zusammenfassung

Englisch

Background Ultrasonic scalpel (UC) and monopolar electrocautery (ME) are common tools for soft tissue dissection. However, morphological data on the related tissue alteration are discordant. We developed an automatic device for standardized sample excision and compared quality and depth of morphological changes caused by UC and ME in a pig model. Methods 100 tissue samples (5 × 3 cm) of the abdominal wall were excised in 16 pigs. Excisions were randomly performed manually or by using the self-constructed automatic device at standard power levels (60 W cutting in ME, level 5 in UC) for abdominal surgery. Quality of tissue alteration and depth of coagulation necrosis were examined histopathologically. Device (UC vs. ME) and mode (manually vs. automatic) effects were studied by two-way analysis of variance at a significance level of 5%. Results At the investigated power level settings UC and ME induced qualitatively similar coagulation necroses. Mean depth of necrosis was 450.4 ± 457.8 μm for manual UC and 553.5 ± 326.9 μm for automatic UC versus 149.0 ± 74.3 μm for manual ME and 257.6 ± 119.4 μm for automatic ME. Coagulation necrosis was significantly deeper (p < 0.01) when UC was used compared to ME. The mode of excision (manual versus automatic) did not influence the depth of necrosis (p = 0.85). There was no significant interaction between dissection tool and mode of excision (p = 0.93). Conclusions Thermal injury caused by UC and ME results in qualitatively similar coagulation necrosis. The depth of necrosis is significantly greater in UC compared to ME at investigated standard power levels.

Keywords: Ultrasonic scalpel; monopolar electrocautery; soft tissue dissection; coagulation necrosis