Histologische Klassifikation für degenerativ geschädigte Menisken - die Wnt-Signalwegsmoleküle RSPO2 und SFRP2 in humanem Meniskusgewebe
Histological classification for degenerative meniscus - the wnt modulating proteins RSPO2 and SFRP2 in human meniscus tissue
by Moritz Roth
Date of Examination:2014-02-10
Date of issue:2014-02-07
Advisor:Prof. Dr. Nicolai Miosge
Referee:PD Dr. Martin Wachowski
Referee:Prof. Dr. Rainer Mausberg
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Abstract
English
This work shows a new histological classification for the degenerative meniscus via alcian blue staining. Speciment were taken from patients, who undergo total knee replacemt operation. We also prove the existance of the wnt modulating molecules RSPO2 and SFRP2 in the adult human meniscus tissue.
Keywords: meniscus; osteoarthritis; RSPO2; SFRP2; wnt
Schlagwörter: Meniskus; Arthrose; RSPO2; SFRP2; wnt