dc.contributor.advisor | Trümper, Lorenz Prof. Dr. | |
dc.contributor.author | Troendlin, Florian | |
dc.date.accessioned | 2014-06-24T08:38:52Z | |
dc.date.available | 2014-07-16T22:50:05Z | |
dc.date.issued | 2014-06-24 | |
dc.identifier.uri | http://hdl.handle.net/11858/00-1735-0000-0022-5EF4-9 | |
dc.identifier.uri | http://dx.doi.org/10.53846/goediss-4558 | |
dc.language.iso | deu | de |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/ | |
dc.subject.ddc | 610 | de |
dc.title | Einsatz von Vibrationstraining als supportive Maßnahme begleitend zu allogenen hämatopoetischen Stammzelltransplantationen. Pilotstudie zu Sicherheit, Machbarkeit und Effektivität | de |
dc.type | doctoralThesis | de |
dc.title.translated | Use of vibration training as a supportive measure concomitantly allogeneic hematopoietic stem cell transplantation. Pilot study on safety, feasibility and effectiveness | de |
dc.contributor.referee | Niklas, André Prof. Dr. | |
dc.date.examination | 2014-07-09 | |
dc.description.abstracteng | In this prospective, randomized pilot study the feasibility, safety and effectiveness of vibration training (every 2 days) for patients, who undergo an allogeneic hematopoietic stem cell transplantation (allo-HSCT) during this training, was investigated. In the present thesis 26 patients were divided randomly into 2 groups: a vibration intervention group receiving conventional physiotherapy and additional vibration training and a control group only receiving conventional physiotherapy. Between these two groups the influence of the treatment on muscle strength, functional performance, QOL and clinical outcome was compared. .
This pilot study showed that vibration training in compliance with the exclusion criteria in the context of allo-HSCT is safe, feasible and effective with a training participation of 83%. Despite significantly more frequent general physiotherapy in the control group (p = 0.005), the study showed a trend that vibration training had a greater influence on strengthen the leg strength (comparison of "hospitalization" with "release": eg control -15%, intervention +6.9% at 180 ° / s extension, p = 0, 07) in the isokinetic testing of the dominant leg extension and flexion as well as on muscular endurance. Increased endurance performance in the Six-Minute Walk Test compared with the control group was not achieved. In the EORTC QLQ C-30, a significant loss of quality of life (p = 0.04) and physical function (p = 0.02) was shown in the total cohort. However, a trend towards less burden of pain could be shown for the intervention group (p = 0.05). | de |
dc.contributor.coReferee | Schön, Margarete Prof. Dr. | |
dc.subject.ger | Vibrationstraining | de |
dc.subject.ger | allogene hämatopoetische Stammzelltransplantation | de |
dc.subject.ger | Lebensqualität | de |
dc.subject.eng | vibration training | de |
dc.subject.eng | allogeneic SCT | de |
dc.subject.eng | exercise | de |
dc.subject.eng | quality of life | de |
dc.subject.eng | physical and functional capacity | de |
dc.identifier.urn | urn:nbn:de:gbv:7-11858/00-1735-0000-0022-5EF4-9-9 | |
dc.affiliation.institute | Medizinische Fakultät | de |
dc.subject.gokfull | Medizin (PPN619874732) | de |
dc.description.embargoed | 2014-07-16 | |
dc.identifier.ppn | 788716298 | |