Expressionsanalyse chondrogener Progenitorzellen im ex-vivo Migrationsexperiment

Expressionsanalyse chondrogener Progenitorzellen im ex-vivo Migrationsexperiment

Expression analysis of chondrogenic progenitor cells in ex-vivo migration experiment

Wagner, Gunar Joachim

Dissertation

Angenommen am: 2015-05-18

Erschienen: 2015-04-30

Betreuer: Miosge, Nicolai Prof. Dr.

Gutachter: Miosge, Nicolai Prof. Dr.

Gutachter: Guan-schmidt, Kaomei PD Dr.

Zum Verlinken/Zitieren: http://hdl.handle.net/11858/00-1735-0000-0022-5FC8-5

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Name: Dissertation_GW 5.pdf

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Zusammenfassung

Englisch

The chondrogenic progenitor cells are under control of the expression factors Sox9 and Runx2 favoritising either chondrogenic or osteogenic behavior. In this study we examine the impact on chondrogenic progenitor cells with a Runx2 knockdown. Using a migration experiment we could analyse the expression of collagen typ 1 and 2 of that cells.

Keywords: regenerative medicine