| dc.contributor.advisor | Ackermann, Lutz Prof. Dr. | |
| dc.contributor.author | Ma, Wenbo | |
| dc.date.accessioned | 2015-05-13T08:07:27Z | |
| dc.date.available | 2015-05-13T08:07:27Z | |
| dc.date.issued | 2015-05-13 | |
| dc.identifier.uri | http://hdl.handle.net/11858/00-1735-0000-0022-5FDF-4 | |
| dc.identifier.uri | http://dx.doi.org/10.53846/goediss-5070 | |
| dc.language.iso | eng | de |
| dc.publisher | Niedersächsische Staats- und Universitätsbibliothek Göttingen | de |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/ | |
| dc.subject.ddc | 540 | de |
| dc.title | Transition Metal-Catalyzed C-H Functionalization for Sustainable Syntheses of Alkenes and Heterocycles | de |
| dc.type | doctoralThesis | de |
| dc.contributor.referee | Ackermann, Lutz Prof. Dr. | |
| dc.date.examination | 2015-05-04 | |
| dc.description.abstracteng | The rapid progress of C–H functionalization chemistry over the last decade has provided numerous efficient protocols for forming new chemical bonds. Especially, the ruthenium(II)-catalyzed direct C–H alkenylations and annulations have been proven viable with a broad substrates scope and excellent chemo-, regio-, and site-selectivity. These carboxylate-assisted ruthenium(II)-catalyzed C–H functionalizations were even allowed in an aerobic fashion with Cu(OAc)2•H2O under an atmosphere of ambient air. Yet, less expensive first-row transition metal complexes such as cobalt salts were also identified as versatile catalysts for step-economical chelation-assisted direct C−H alkenylations in user-friendly solvent. This Co(OAc)2 catalyst can enable the transformation smoothly with a widely range functional groups tolerance, to furnish the isoindolin-1-ones in high yields. In the last project, we developed silver-mediated alkyne annulations by C–H/P–H functionalizations. This transformation proceeded with excellent chemo- and site-selectivities in the presence of silver acetate as the terminal oxidant, thereby furnishing substituted phosphindole with broad scope. The radical mechanism of the C–H/C–P functionalization was unraveled though detailed mechanistic studies. | de |
| dc.contributor.coReferee | Stalke, Dietmar Prof. Dr. | |
| dc.subject.eng | Transition Metal-Catalysis, Directing Group, Alkenylation, Annulation | de |
| dc.identifier.urn | urn:nbn:de:gbv:7-11858/00-1735-0000-0022-5FDF-4-0 | |
| dc.affiliation.institute | Fakultät für Chemie | de |
| dc.subject.gokfull | Chemie (PPN62138352X) | de |
| dc.identifier.ppn | 825483409 | |