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dc.contributor.advisor Ackermann, Lutz Prof. Dr.
dc.contributor.author Ma, Wenbo
dc.date.accessioned 2015-05-13T08:07:27Z
dc.date.available 2015-05-13T08:07:27Z
dc.date.issued 2015-05-13
dc.identifier.uri http://hdl.handle.net/11858/00-1735-0000-0022-5FDF-4
dc.language.iso eng de
dc.publisher Niedersächsische Staats- und Universitätsbibliothek Göttingen de
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/
dc.subject.ddc 540 de
dc.title Transition Metal-Catalyzed C-H Functionalization for Sustainable Syntheses of Alkenes and Heterocycles de
dc.type doctoralThesis de
dc.contributor.referee Ackermann, Lutz Prof. Dr.
dc.date.examination 2015-05-04
dc.description.abstracteng The rapid progress of C–H functionalization chemistry over the last decade has provided numerous efficient protocols for forming new chemical bonds. Especially, the ruthenium(II)-catalyzed direct C–H alkenylations and annulations have been proven viable with a broad substrates scope and excellent chemo-, regio-, and site-selectivity. These carboxylate-assisted ruthenium(II)-catalyzed C–H functionalizations were even allowed in an aerobic fashion with Cu(OAc)2•H2O under an atmosphere of ambient air. Yet, less expensive first-row transition metal complexes such as cobalt salts were also identified as versatile catalysts for step-economical chelation-assisted direct C−H alkenylations in user-friendly solvent. This Co(OAc)2 catalyst can enable the transformation smoothly with a widely range functional groups tolerance, to furnish the isoindolin-1-ones in high yields. In the last project, we developed silver-mediated alkyne annulations by C–H/P–H functionalizations. This transformation proceeded with excellent chemo- and site-selectivities in the presence of silver acetate as the terminal oxidant, thereby furnishing substituted phosphindole with broad scope. The radical mechanism of the C–H/C–P functionalization was unraveled though detailed mechanistic studies. de
dc.contributor.coReferee Stalke, Dietmar Prof. Dr.
dc.subject.eng Transition Metal-Catalysis, Directing Group, Alkenylation, Annulation de
dc.identifier.urn urn:nbn:de:gbv:7-11858/00-1735-0000-0022-5FDF-4-0
dc.affiliation.institute Fakultät für Chemie de
dc.subject.gokfull Chemie  (PPN62138352X) de
dc.identifier.ppn 825483409

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