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Einfluss von Wachstumsfaktoren auf die Migration von mesenchymalen Progenitorzellen im menschlichen Kniemeniskus

Influence of Growth Factors on the migration of mesenchymal progenitor cells in the human knee meniscus

Claus von der Burchard
Doctoral thesis
Date of Examination: 2015-07-07
Date of issue: 2015-07-07
Advisor: Miosge, Nicolai Prof. Dr.
Referee: Miosge, Nicolai Prof. Dr.
Referee: Behr, Rüdiger PD Dr.

Persistent Address: http://hdl.handle.net/11858/00-1735-0000-0022-6049-0

 

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Abstract

English

Meniscal Progenitor Cells (MPCs) are a newly established group of progenitor cells found in knee menisci of patients suffering from osteoarthritis. This work compares the influence of three growth factors on the migration of these cells: PDGF, EGF, IGF-1.
Keywords: meniscus; mesenchymal stem cell; progenitor cell; migration; pdgf; egf; igf-1; msc
Schlagwörter: Meniskus; Mesenchymale Stammzelle; msc; Migration; pdgf; igf-1; egf
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