Inzidenz, Einflussgrößen und Folgen der unbeabsichtigten perioperativen Hypothermie während lungenchirurgischer Operationen: Eine retrospektive Analyse

Gries, Gereon Maria Johannes

dc.contributor.advisor	Bräuer, Anselm Prof. Dr.
dc.contributor.author	Gries, Gereon Maria Johannes
dc.date.accessioned	2015-09-03T08:57:04Z
dc.date.available	2015-09-29T22:50:06Z
dc.date.issued	2015-09-03
dc.identifier.uri	http://hdl.handle.net/11858/00-1735-0000-0023-3DA2-9
dc.identifier.uri	http://dx.doi.org/10.53846/goediss-5248
dc.identifier.uri	http://dx.doi.org/10.53846/goediss-5248
dc.identifier.uri	http://dx.doi.org/10.53846/goediss-5248
dc.language.iso	deu	de
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.ddc	610	de
dc.title	Inzidenz, Einflussgrößen und Folgen der unbeabsichtigten perioperativen Hypothermie während lungenchirurgischer Operationen: Eine retrospektive Analyse	de
dc.type	doctoralThesis	de
dc.title.translated	Incidence, influential variables and sequelae of inadvertent perioperative hypothermia in the course of lung surgery: A retrospective analysis	de
dc.contributor.referee	Bräuer, Anselm Prof. Dr.
dc.date.examination	2015-09-22
dc.description.abstracteng	Inadvertent perioperative hypothermia is a common event in the course of surgical interventions and aggravates perioperative morbidity among others by impairment of hemostasis and wound healing. Furthermore, it is associated with an increased risk of ischemic cardiac events. Nonetheless, little is known about the relevance and influential variables particularly with regard to the chosen anesthetic and surgical techniques. Influential variables of incidence and extent of perioperative hypothermia in the course of lung surgery are supposed to be identified in this publication. In addition, incidence of perioperative hypothermia is quantified and implication of perioperative morbidity and mortality shall be investigated. The analysis of 339 patients reveals an incidence of 64,3%. Based on multivariate analysis, time for anesthetic induction (p=0,004) becomes apparent as a facilitating variable, whereas larger body surface area (p=0,006) and the presence of pulmonary disease (p=0,007) decrease the incidence. Extent of perioperative hypothermia, determined by lowest perioperative temperature, is - in addition to anesthetic induction time (p=0,010) - negatively influenced by intraoperative infused volume (p=0,005), epidural anesthesia (p=0,002) and execution of the procedure by means of video-assisted thoracoscopic surgery (p=0,011). As opposed to this, larger body mass index (p=<0,001) and impairment of pulmonary function (p=0,008) have positive influence. However, there is no difference apparent between perioperative normothermic and hypothermic patients regarding transfusion, necessity and duration of mechanical ventilation and length of stay on the intensive care unit. Nevertheless, patients that suffered perioperative hypothermia were discharged from hospital earlier (p=0,012). There was no difference found regarding mortality during hospitalization. Despite the methodical deficiency of a retrospective analysis, especially the influence of anesthetic induction time and impairment of pulmonary function shown here mean promising origin for further research. More particularly, the negative influence of video-assisted thoracoscopic surgery demands more clarification.	de
dc.contributor.coReferee	Danner, Bernhard C. PD Dr.
dc.contributor.thirdReferee	Unterberg-Buchwald, Christina Prof. Dr.
dc.subject.ger	Unbeabsichtigte Hypothermie	de
dc.subject.ger	Perioperative Versorgung	de
dc.subject.ger	Lungenchirurgie	de
dc.subject.ger	Epiduralanästhesie	de
dc.subject.ger	VATS	de
dc.subject.eng	Accidential Hypothermia	de
dc.subject.eng	Perioperative Care	de
dc.subject.eng	Pulmonary Surgical Procedures	de
dc.subject.eng	Epidural Anesthesia	de
dc.subject.eng	VATS	de
dc.identifier.urn	urn:nbn:de:gbv:7-11858/00-1735-0000-0023-3DA2-9-5
dc.affiliation.institute	Medizinische Fakultät	de
dc.subject.gokfull	Medizin (PPN619874732)	de
dc.subject.gokfull	Anästhesiologie / Intensivmedizin / Notfallmedizin / Analgesie - Allgemein- und Gesamtdarstellungen (PPN619875917)	de
dc.description.embargoed	2015-09-29
dc.identifier.ppn	835856801

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Human- und Zahnmedizin [2872]

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