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Differenzielle Expression proatherogener Zellmarker auf Monozytensubpopulationen bei Patienten mit stabiler koronarer Herzkrankheit

dc.contributor.advisorCzepluch, Frauke Stefanie PD Dr.
dc.contributor.authorKuschicke, Hendrik
dc.date.accessioned2017-03-29T08:40:57Z
dc.date.available2017-04-06T22:50:06Z
dc.date.issued2017-03-29
dc.identifier.urihttp://hdl.handle.net/11858/00-1735-0000-0023-3DF4-2
dc.identifier.urihttp://dx.doi.org/10.53846/goediss-6210
dc.language.isodeude
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.ddc610de
dc.titleDifferenzielle Expression proatherogener Zellmarker auf Monozytensubpopulationen bei Patienten mit stabiler koronarer Herzkrankheitde
dc.typedoctoralThesisde
dc.title.translatedDifferential expression of proatherogenic cell markers on monocyte subpopulations of patients with stable coronary artery diseasede
dc.contributor.refereeCzepluch, Frauke Stefanie PD Dr.
dc.date.examination2017-03-30
dc.description.abstractengMonocytes and platelets are important cellular mediators of atherosclerosis. Human monocytes can be divided into CD14++CD16− , CD14++CD16+ and CD14+CD16++ cells, which differ in their functional properties. The aim of this thesis was to examine monocyte subset distribution, monocyte-platelet aggregate (MPA) formation, expression of CCR5, the receptor of the platelet-derived chemokine CCL5, of OPN receptor CD44, monocyte migration chemokine, of KLF4, an atheroprotective protein, and other soluble chemokines, to determine whether these parameters are altered in individuals with coronary atherosclerosis.de
dc.contributor.coRefereeOppermann, Martin Prof. Dr.
dc.contributor.thirdRefereeMeyer, Thomas Prof. Dr.
dc.subject.engcoronary artery diseasede
dc.subject.engmonocyte subsetsde
dc.subject.engmonocyte subpopulationsde
dc.subject.engMPAde
dc.subject.engOPNde
dc.subject.engCCR5de
dc.subject.engCCL5de
dc.subject.engRANTESde
dc.identifier.urnurn:nbn:de:gbv:7-11858/00-1735-0000-0023-3DF4-2-8
dc.affiliation.instituteMedizinische Fakultätde
dc.subject.gokfullKardiologie (PPN619875755)de
dc.description.embargoed2017-04-06
dc.identifier.ppn883570882


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