Zur Kurzanzeige

Small Molecule Activation of Copper and Iron Complexes with Bis(oxazoline) Ligands

dc.contributor.advisorMeyer, Franc Prof. Dr.
dc.contributor.authorGoswami, Vandana Esther
dc.date.accessioned2017-09-22T08:05:16Z
dc.date.available2017-09-22T08:05:16Z
dc.date.issued2017-09-22
dc.identifier.urihttp://hdl.handle.net/11858/00-1735-0000-0023-3F0E-B
dc.identifier.urihttp://dx.doi.org/10.53846/goediss-6498
dc.language.isoengde
dc.publisherNiedersächsische Staats- und Universitätsbibliothek Göttingende
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.ddc540de
dc.titleSmall Molecule Activation of Copper and Iron Complexes with Bis(oxazoline) Ligandsde
dc.typedoctoralThesisde
dc.contributor.refereeMeyer, Franc Prof. Dr.
dc.date.examination2016-10-17
dc.description.abstractengThis work describes small molecule activation by copper and iron complexes with structurally and electronically modified bis(oxazoline) (BOX) ligand systems, focusing on dioxygen and nitric oxide as substrates. Dioxygen activation at low temperatures by copper(I) complexes with neutral BOX scaffolds generated the side on peroxo dicopper(II) systems that resemble the intermediates found in type III copper proteins, whereas those complexes with an anionic BOX-derived scaffold generated the bis(µ-oxido) dicopper(III) species. The bis(µ-oxido) system has recently been proposed as an active intermediate of pMMO. All complexes have been comprehensively characterized in solid state and solution, including single crystal X-ray crystallographic structure determination for representative examples, and the intermediates were screened for substrate reactivity. Moreover, triggered by protonation/deprotonation reactions, it was possible to interconvert the side-on peroxo dicopper(II) and bis(µ-oxido) dicopper(III) systems. The reaction of iron(II) BOX complexes with nitric oxide successfully generated a dinitrosyl iron complex that was isolated and characterized as well. In conclusion, BOX ligands that have been termed as a privileged ligand class in the field of asymmetric catalysis, have proved themselves to be useful in the field of bioinorganic chemistry as well.de
dc.contributor.coRefereeSiewert, Inke Dr.
dc.subject.engsmall molecule activationde
dc.subject.engtype III copper proteinsde
dc.subject.engside-on peroxo dicopper(II)de
dc.subject.engbis mu-oxido dicopper(III)de
dc.subject.engnitric oxidede
dc.subject.engdinitrosyl iron complexde
dc.subject.engbis(oxazoline)de
dc.identifier.urnurn:nbn:de:gbv:7-11858/00-1735-0000-0023-3F0E-B-4
dc.affiliation.instituteFakultät für Chemiede
dc.subject.gokfullChemie  (PPN62138352X)de
dc.identifier.ppn1004916434 100014769X


Dateien

Thumbnail

Das Dokument erscheint in:

Zur Kurzanzeige