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dc.contributor.advisor Parlitz, Ulrich Prof. Dr.
dc.contributor.author Stein, Sebastian
dc.date.accessioned 2017-11-22T10:44:39Z
dc.date.available 2017-11-22T10:44:39Z
dc.date.issued 2017-11-22
dc.identifier.uri http://hdl.handle.net/11858/00-1735-0000-0023-3F7A-6
dc.language.iso eng de
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.ddc 530 de
dc.title Synchronisation Behaviour of Viscoelastically Coupled Self-Sustained Oscillators as Models for Oscillations of Premature Cardiomyocytes de
dc.type doctoralThesis de
dc.contributor.referee Kree, Reiner Prof. Dr.
dc.date.examination 2017-10-16
dc.subject.gok Physik (PPN621336750) de
dc.description.abstracteng This thesis analyses how the synchronisation behaviour of self-sustained oscillators is influenced by the viscoelastic properties of their coupling. This question is motivated by the early development stage of artificial heart tissue in which the synchronisation of beating premature cardiomyocytes is aided by the viscoelastic polymer gel surrounding them. To tackle this task, a mathematical model is developed which comprises self-sustained oscillators and a viscoelastic component providing their coupling. Techniques and concepts from nonlinear dynamics are used to study the stability of the synchronous states featured by that model. Furthermore, first experimental insights are provided and analysed which characterise the model system of the premature state of the engineered heart muscle. de
dc.contributor.coReferee Parlitz, Ulrich Prof. Dr.
dc.subject.eng viscoelastic coupling de
dc.subject.eng Maxwell model de
dc.subject.eng synchronisation de
dc.subject.eng Van der Pol oscillator de
dc.subject.eng premature cardiomyocytes de
dc.identifier.urn urn:nbn:de:gbv:7-11858/00-1735-0000-0023-3F7A-6-4
dc.affiliation.institute Fakultät für Physik de
dc.identifier.ppn 100545776X

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