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Synchronisation Behaviour of Viscoelastically Coupled Self-Sustained Oscillators as Models for Oscillations of Premature Cardiomyocytes

dc.contributor.advisorParlitz, Ulrich Prof. Dr.
dc.contributor.authorStein, Sebastian
dc.date.accessioned2017-11-22T10:44:39Z
dc.date.available2017-11-22T10:44:39Z
dc.date.issued2017-11-22
dc.identifier.urihttp://hdl.handle.net/11858/00-1735-0000-0023-3F7A-6
dc.identifier.urihttp://dx.doi.org/10.53846/goediss-6600
dc.language.isoengde
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.ddc530de
dc.titleSynchronisation Behaviour of Viscoelastically Coupled Self-Sustained Oscillators as Models for Oscillations of Premature Cardiomyocytesde
dc.typedoctoralThesisde
dc.contributor.refereeKree, Reiner Prof. Dr.
dc.date.examination2017-10-16
dc.subject.gokPhysik (PPN621336750)de
dc.description.abstractengThis thesis analyses how the synchronisation behaviour of self-sustained oscillators is influenced by the viscoelastic properties of their coupling. This question is motivated by the early development stage of artificial heart tissue in which the synchronisation of beating premature cardiomyocytes is aided by the viscoelastic polymer gel surrounding them. To tackle this task, a mathematical model is developed which comprises self-sustained oscillators and a viscoelastic component providing their coupling. Techniques and concepts from nonlinear dynamics are used to study the stability of the synchronous states featured by that model. Furthermore, first experimental insights are provided and analysed which characterise the model system of the premature state of the engineered heart muscle.de
dc.contributor.coRefereeParlitz, Ulrich Prof. Dr.
dc.subject.engviscoelastic couplingde
dc.subject.engMaxwell modelde
dc.subject.engsynchronisationde
dc.subject.engVan der Pol oscillatorde
dc.subject.engpremature cardiomyocytesde
dc.identifier.urnurn:nbn:de:gbv:7-11858/00-1735-0000-0023-3F7A-6-4
dc.affiliation.instituteFakultät für Physikde
dc.identifier.ppn100545776X


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