In-vivo-Untersuchungen der axonalen Degeneration im Tiermodell der Multiplen Sklerose

In-vivo research of axonal degeneration in an animal modell of multiple sclerosis

by Johannes Ruhe
Doctoral thesis
Date of Examination:2017-12-19
Date of issue:2017-12-08
Advisor:Prof. Dr. Katharina Hein
Referee:Prof. Dr. Katharina Hein
Referee:PD Dr. Imke Metz
Persistent Address: http://dx.doi.org/10.53846/goediss-6637

 

 

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Abstract

English

We established a new rat modell for in-vivo research of axonal degeneration in the experimental autoimmune encephalomyelitis (eae). The modell offers to observe the degeneration of single axons in the optic nerv by using fluorescence microscopy.
Keywords: eae + mog-eae + fluorescence + degeneration + optic nerv + rat
 
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