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Geschlechtsspezifische Unterschiede sprechassoziierter Gehirnaktivität bei stotternden Menschen

Eine klinische Studie mittels funktioneller Magnetresonanztomografie

dc.contributor.advisorSommer, Martin Prof. Dr.
dc.contributor.authorBütfering, Christoph
dc.titleGeschlechtsspezifische Unterschiede sprechassoziierter Gehirnaktivität bei stotternden Menschende
dc.title.alternativeEine klinische Studie mittels funktioneller Magnetresonanztomografiede
dc.title.translatedGender-specific speech-associated differences in brain activation of people who stutterde
dc.contributor.refereeSommer, Martin Prof. Dr.
dc.description.abstractengThis clinical trial used functional magnetic resonance imaging to explore gender-specific differences during imagined speaking and singing in people who stutter. 15 women who stutter, 16 men who stutter, 17 women who do not stutter and 17 men who do not stutter have been examined. The task was to notionally repeat the months of the year and the “Kleine Nachtmusik” by Mozart. Comparing all participants who stutter with all participants who not stutter we found right-hemispheric overactivations in the stuttering individuals during imagined speaking that where located fronto-operculo-insular. This effect was caused by the women who stutter who showed these overactivations in comparison to the women who not stutter. It is therefore a stutter- and gender-specific effect of the women who stutter and this region seems to be jointly responsible for the persistence of stuttering in stuttering women. Contrary to previous findings the men who stutter showed no significant differences in comparison to the men who not stutter. Comparing the men who stutter with the women who stutter the men who stutter showed overactivations within the Precuneus as well during imagined speaking as during imagined singing. These precuneal overactivations were positively correlated with a lesser degree of the stuttering symptoms as well in men who stutter as in women who stutter. Only in men who stutter we found a positive correlation between activations of the precuneus and a high degree of self-efficacy (agency) concerning the individual ability to fluent speaking. Thus the Precuneus seems to be a region that is strongly associated with stuttering especially in men who stutter. During imagined singing the participants who stutter didn't show significant differences of brain activation patterns compared to the participants who do not stutter. de
dc.contributor.coRefereeJordan, Kirsten Dr.
dc.title.alternativeTranslatedA clinical trial using functional magnetic resonance tomographyde
dc.subject.geridiopathisches Stotternde
dc.subject.gerHirnaktivierungsmuster während Sprechen und Singende
dc.subject.gergeschlechtsspezifische Unterschiede sprechassoziierter Gehirnaktivitätde
dc.subject.gerfunktionelle Magnetresonanztomografiede
dc.subject.engspeech-associated brain activation patternsde
dc.subject.engbrain activation during speaking and hummingde
dc.subject.engfunctional magnetic resonance imagingde
dc.affiliation.instituteMedizinische Fakultätde
dc.subject.gokfullMedizin (PPN619874732)de
dc.subject.gokfullNeurologie - Allgemein- und Gesamtdarstellungen (PPN619876247)de

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