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Analysis of early steps in Assembly of Cytochrome c Oxidase

dc.contributor.advisorRehling, Peter Prof. Dr.
dc.contributor.authorBareth, Bettina
dc.date.accessioned2014-12-18T09:23:44Z
dc.date.available2014-12-18T09:23:44Z
dc.date.issued2014-12-18
dc.identifier.urihttp://hdl.handle.net/11858/00-1735-0000-0023-996C-C
dc.identifier.urihttp://dx.doi.org/10.53846/goediss-4834
dc.language.isoengde
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/
dc.subject.ddc572de
dc.titleAnalysis of early steps in Assembly of Cytochrome c Oxidasede
dc.typedoctoralThesisde
dc.contributor.refereeRehling, Peter Prof. Dr.
dc.date.examination2014-02-26
dc.description.abstractengCytochrome c oxidase (COX) is the terminal enzyme of the respiratory chain. Due to its multimeric nature, assembly and maturation requires the concerted action of over 20 assembly factors in yeast. COX is composed of both nuclear- and mitochondria-encoded protein subunits. Its catalytic core is formed by three mitochondria-encoded subunits (Cox1, Cox2 and Cox3) harboring essential prosthetic groups. This study analysed different stages during early cytochrome c oxidase assembly steps and extends the understanding of this process.de
dc.contributor.coRefereeJakobs, Stefan Prof. Dr.
dc.subject.engmitochondriade
dc.subject.engrespiratory chainde
dc.subject.engCOX assemblyde
dc.subject.engCox1 maturationde
dc.subject.engheme synthase Cox15de
dc.identifier.urnurn:nbn:de:gbv:7-11858/00-1735-0000-0023-996C-C-8
dc.affiliation.instituteGöttinger Graduiertenschule für Neurowissenschaften, Biophysik und molekulare Biowissenschaften (GGNB)de
dc.subject.gokfullBiologie (PPN619462639)de
dc.identifier.ppn813035716


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