Wirkung von kurzzeitiger vertikaler Ganzkörpervibration mit Frequenzen unter 90 Hz auf das Femur ovarektomierter Ratten.

Neuerburg, Theresa Elisabeth Adele

dc.contributor.advisor	Tezval, Mohammad PD Dr.
dc.contributor.author	Neuerburg, Theresa Elisabeth Adele
dc.date.accessioned	2015-11-27T10:14:59Z
dc.date.available	2015-12-21T23:50:05Z
dc.date.issued	2015-11-27
dc.identifier.uri	http://hdl.handle.net/11858/00-1735-0000-0028-8647-D
dc.identifier.uri	http://dx.doi.org/10.53846/goediss-5392
dc.language.iso	deu	de
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.ddc	610	de
dc.title	Wirkung von kurzzeitiger vertikaler Ganzkörpervibration mit Frequenzen unter 90 Hz auf das Femur ovarektomierter Ratten.	de
dc.type	doctoralThesis	de
dc.title.translated	Effect of vertical, short-term whole-body vibration with frequencies under 90 Hz on the femur of ovariectomized rats.	de
dc.contributor.referee	Wiese, Karl Günter Prof. Dr. Dr.
dc.date.examination	2015-12-14
dc.description.abstracteng	SUMMARY: In this study, short-term, verticale whole-body Vibration (WBV) at 35 Hz, 50 Hz, 70 Hz and 90 Hz was testet to trabecular bone quality, Rigidity and Densitiy on the femur of the osteoporotic rat. We saw an improvement of trabecular bone quality, rigidity and density in xxxxx. These results may lead to the thesis, that the treatment tested in this study may be an attractive treatment of osteoporosis. INTRODUCTION: Beside the pharmacological options to treat Osteoporosis, physical exercise is known to strengthen bone mass. In our study we investigate, the effects of vertical WBV on bone quality, rigidity and density, using an osteoporotic rat model. METHODS: Ninety female Sprague Dawley rats were divides into 6 groups of 15 rats. At the age of three month group 2 to 6 was ovariectomized, whereas group 1 served as a control group. Group 2 to 6 received WBV at 35Hz, 50 Hz, 70 Hz and 90 Hz for 30 days. After sacrificing the rats, we evaluated femoral bone strength, histomorphometric parameters and bone mineral density (BMD). RESULTS: Treatment with vertical WBV at frequencies of 35 Hz and 70 Hz resulted in improved biomechanical properties, whereas the vibration with 90 Hz showed a reduction the parameters tested. CONCLUSION: Using WBV as a non-pharmacological Option to treat osteoporosis may lead to an enhancement of bone strength and bone mass. There are still studies to be continued to evaluate the most effective length of treatment and frequencie (Hz) to maximize osteoporotic bone strength.	de
dc.contributor.coReferee	Mausberg, Rainer Prof. Dr.
dc.subject.ger	Osteoporose	de
dc.subject.ger	Ratte	de
dc.subject.ger	Femur	de
dc.subject.ger	Knochenstärke	de
dc.subject.ger	Ganzkörpervibration	de
dc.subject.eng	osteoporosis	de
dc.subject.eng	rat	de
dc.subject.eng	femur	de
dc.subject.eng	whole-body vibration	de
dc.subject.eng	bone strength	de
dc.identifier.urn	urn:nbn:de:gbv:7-11858/00-1735-0000-0028-8647-D-6
dc.affiliation.institute	Medizinische Fakultät	de
dc.subject.gokfull	Medizin (PPN619874732)	de
dc.subject.gokfull	Unfallchirurgie (PPN619876018)	de
dc.description.embargoed	2015-12-21
dc.identifier.ppn	841076901

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