• Deutsch
    • English
  • English 
    • Deutsch
    • English
  • Login
Item View 
  •   Home
  • Medizin
  • Human- und Zahnmedizin
  • Item View
  •   Home
  • Medizin
  • Human- und Zahnmedizin
  • Item View
JavaScript is disabled for your browser. Some features of this site may not work without it.

Parakrine Beeinflussung der Genexpression in vitro von chondrogenen Zellen in der Osteoarthrose

Paracrine modulation of the gene-expression in vitro of chondrogenic cells in osteoarthritis

by Phillip Marks
Doctoral thesis
Date of Examination:2016-03-23
Date of issue:2016-03-22
Advisor:Prof. Dr. Nicolai Miosge
Referee:Prof. Dr. Rüdiger Behr
Referee:Prof. Dr. Margarete Schön
crossref-logoPersistent Address: http://dx.doi.org/10.53846/goediss-5578

 

 

Files in this item

Name:Promotion PM finalisiert.pdf
Size:1.28Mb
Format:PDF
ViewOpen

The following license files are associated with this item:


Abstract

English

Analysis of the gene-Expression profiles of mesenchymal stem cells (MSC), chondrogenic progenitor cells (CPC) and Chondrocytes in 3D-Coculture-Systems and in conditions with osteoarthrotic conditioned culture media. The results show CPC in similar potential of paracrine Mediation as MSC. Further we could prove indifferent trophic mediation of osteoarthritic cartilage independently from the grade of degradation.
Keywords: mesenchymal stem cells; chondrogenic progenitor cells; cartilage; paracrine; gene expression
Schlagwörter: Osteoarthrose; Mesenchymale Stammzellen; Chondrogene Progenitorzellen; Genexpression; parakrin; Gelenkknorpel
 

Statistik

Publish here

Browse

All of eDissFaculties & ProgramsIssue DateAuthorAdvisor & RefereeAdvisorRefereeTitlesTypeThis FacultyIssue DateAuthorAdvisor & RefereeAdvisorRefereeTitlesType

Help & Info

Publishing on eDissPDF GuideTerms of ContractFAQ

Contact Us | Impressum | Cookie Consents | Data Protection Information | Accessibility
eDiss Office - SUB Göttingen (Central Library)
Platz der Göttinger Sieben 1
Mo - Fr 10:00 – 12:00 h


Tel.: +49 (0)551 39-27809 (general inquiries)
Tel.: +49 (0)551 39-28655 (open access/parallel publications)
ediss_AT_sub.uni-goettingen.de
[Please replace "_AT_" with the "@" sign when using our email adresses.]
Göttingen State and University Library | Göttingen University
Medicine Library (Doctoral candidates of medicine only)
Robert-Koch-Str. 40
Mon – Fri 8:00 – 24:00 h
Sat - Sun 8:00 – 22:00 h
Holidays 10:00 – 20:00 h
Tel.: +49 551 39-8395 (general inquiries)
Tel.: +49 (0)551 39-28655 (open access/parallel publications)
bbmed_AT_sub.uni-goettingen.de
[Please replace "_AT_" with the "@" sign when using our email adresses.]