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Die entzündungsmodulierenden Eigenschaften von Adiponektin und Leptin und deren Wirkung auf chondrogene Progenitorzellen

dc.contributor.advisorMiosge, Nicolai Prof. Dr.
dc.contributor.authorJohannsen, Inga
dc.date.accessioned2016-04-08T09:06:28Z
dc.date.available2016-04-20T22:50:12Z
dc.date.issued2016-04-08
dc.identifier.urihttp://hdl.handle.net/11858/00-1735-0000-0028-8727-D
dc.identifier.urihttp://dx.doi.org/10.53846/goediss-5603
dc.identifier.urihttp://dx.doi.org/10.53846/goediss-5603
dc.identifier.urihttp://dx.doi.org/10.53846/goediss-5603
dc.language.isodeude
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.ddc610de
dc.titleDie entzündungsmodulierenden Eigenschaften von Adiponektin und Leptin und deren Wirkung auf chondrogene Progenitorzellende
dc.typedoctoralThesisde
dc.title.translatedInflammatory effects of adiponectin and leptin in chondrogenic progenitor cellsde
dc.contributor.refereeCzepluch, Frauke PD Dr.
dc.date.examination2016-04-13
dc.description.abstractengOsteoarthritis (OA) and rheumatoid arthritis (RA) belong to the most common forms of arthitis worldwide. They are a major cause of disability, resulting in pain and loss of function. The common aspect of both diseases is an increase of inflammatory mediators within the affected joint. These pathologic changes include the affection of circulation mediators released by adipose tissue, known as adipocytokines. In this study we examined the effect of two major adipocytokines, adiponectin and leptin and their interaction with chondrogenic progenitor cells (CPC), derived from human cartilage.de
dc.contributor.coRefereeSchön, Margarete Prof. Dr.
dc.subject.engosteoarthritisde
dc.subject.engrheumatoid arthritisde
dc.subject.engadipocytokinesde
dc.subject.engadiponectinde
dc.subject.engleptinde
dc.identifier.urnurn:nbn:de:gbv:7-11858/00-1735-0000-0028-8727-D-9
dc.affiliation.instituteMedizinische Fakultätde
dc.subject.gokfullZahn-, Mund- und Kieferheilkunde - Allgemein- und Gesamtdarstellungen (PPN619876360)de
dc.description.embargoed2016-04-20
dc.identifier.ppn856518093


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