dc.contributor.advisor | Mausberg, Rainer Prof. Dr. | |
dc.contributor.author | Leuschner, Constanze | |
dc.date.accessioned | 2016-08-01T13:22:25Z | |
dc.date.available | 2016-08-18T22:50:05Z | |
dc.date.issued | 2016-08-01 | |
dc.identifier.uri | http://hdl.handle.net/11858/00-1735-0000-0028-87E4-3 | |
dc.identifier.uri | http://dx.doi.org/10.53846/goediss-5739 | |
dc.identifier.uri | http://dx.doi.org/10.53846/goediss-5739 | |
dc.identifier.uri | http://dx.doi.org/10.53846/goediss-5739 | |
dc.language.iso | deu | de |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.subject.ddc | 610 | de |
dc.title | Klinische Studie zur möglichen Assoziation von Parodontitis und chronisch entzündlichen Darmerkrankungen - Ergebnisse zahnbezogener und parodontologischer Parameter | de |
dc.type | doctoralThesis | de |
dc.title.translated | Clinical study of possible association between periodontitis and chronic bowel disease - results of dental and periodontal parameters | de |
dc.contributor.referee | Cameron, Silke PD Dr. | |
dc.date.examination | 2016-08-11 | |
dc.description.abstracteng | Clinical periodontal and dental parameters in patients with Chronical Bowel Disease
Aim: The aim of this clinical cross-sectional study was to evaluate the periodontal and dental situation of patients with chronical bowel diesease (CBD) compared to healthy control subjects (HC).
Material and Methods: 59 CBD-patients with the diagnosis of Crohn’s disease or ulcerative colitis (49.81 ± 12.1 years, f = 25, m = 34) and 59 HC (51.33 ± 12.0 years, f = 25, m = 34) were included in this study. HC-patients were matched to CBD-patients considering age and gender. Dental examination of all patient groups included: dental findings (DMF-T), papillas bleeding index (PBI) and evaluation of periodontal situation (pocket probing depth [PPD], clinical attachment level [CAL]). Periodontal condition (PPD and/or CAL) was classified into no, mild, moderate or severe periodontitis. In addition oral findings were documented.
Statistical analysis: level of significance: α = 5 %.
Results: The mean DMF-T showed no significant difference between CBD and HC. But the mean D-T was significantly different between CBD and HC (CBD: 0.73 ± 1.9, HC: 0.02 ± 0.1; p = 0.001); CBD-patients showed by trend more M-T than HC (M-T: CBD = 4.36 ± 4.9, HC = 3.66 ± 4.6; p = 0.19). Furthermore, values of PBI (CBD: 1.26 ± 0.8 HC: 0.27 ± 0.4, p < 0,001) and CAL (CBD: 3.32, HC: 2.12, p < 0,0001) were significantly higher for CBD-patients. PPD was not significantly different (CBD: 2.39 ± 0.5, HC: 2.36 ± 0.8; p = 0.81). 42 % of CBD- and 20 % of HC-patients had a severe periodontitis so that the difference of PA was significant (severe: CBD = 25, HC = 12; p = 0.04). Differences between Crohn’s disease and ulcerative colitis could not been observed (p > 0.05). Oral find-ings in CBD-patients were rare and non-specific.
Conclusion: The majority of CBD-patients showed significant higher D-T, PBI, CAL and more severe periodontitis in comparison to HC. | de |
dc.contributor.coReferee | Meyer, Thomas Prof. Dr. | |
dc.subject.ger | Parodontitis | de |
dc.subject.ger | Morbus Crohn | de |
dc.subject.ger | Colitis Ulcerosa | de |
dc.subject.ger | Chronisch entzündliche Darmerkrankung | de |
dc.subject.eng | Periodontitis | de |
dc.subject.eng | Crohn's disease | de |
dc.subject.eng | Ulcerative colitis | de |
dc.subject.eng | Chronical Bowel Disease | de |
dc.identifier.urn | urn:nbn:de:gbv:7-11858/00-1735-0000-0028-87E4-3-3 | |
dc.affiliation.institute | Medizinische Fakultät | de |
dc.subject.gokfull | Medizin (PPN619874732) | de |
dc.description.embargoed | 2016-08-18 | |
dc.identifier.ppn | 869468464 | |