Expression des epidermalen Wachstumsfaktorrezeptors Her2/neu in Rektumkarzinomen des lokal fortgeschrittenen Stadiums UICC II / III - Validierung an Patienten der Phase-III-Studien der German Rectal Cancer Study Group

Expression des epidermalen Wachstumsfaktorrezeptors Her2/neu in Rektumkarzinomen des lokal fortgeschrittenen Stadiums UICC II / III - Validierung an Patienten der Phase-III-Studien der German Rectal Cancer Study Group

Expression of the epidermal growth-factor-receptor Her2/neu in advanced local rectal cancer UICC II / III - validation on patients of the phase-III-studies of the german rectal cancer study group

Marcus Storch

Doctoral thesis

Date of Examination: 2016-09-28

Date of issue: 2016-08-22

Advisor: Conradi, Lena-Christin Dr.

Referee: Liersch, Torsten Prof. Dr.

Referee: Burfeind, Peter Prof. Dr.

Persistent Address: http://hdl.handle.net/11858/00-1735-0000-0028-8808-B

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Abstract

English

Validation of the frequency of the expression of her2/neu in rectal cancer. Her2/neu is an epidermal growth factor receptor known from breast or oesophagus cancer and thought to be a possible therapy target in rectal cancer.

Keywords: rectal cancer; her2/neu; epidermal growth factor receptor; CAO/ARO/AIO-04; CAO/ARO/AIO-94

Schlagwörter: CAO/ARO/AIO-04; Rektumkarzinom; her2/neu; CAO/ARO/AIO-94