Within this thesis, two fragments of the natural product Parnafungin C, a highly functionalized chiral chromane with the correct absolute and relative configuration of all stereogenic centers as well as a biaryl system comprising all required substituents for the formation of the unique isoxazolidinone-moiety, were synthesized. Key steps are an enantioselective Wacker oxidation or a Domino-Wacker/carbonylation/methoxylation reaction, a Sharpless asymmetric dihydroxylation reaction and a Suzuki-Miyaura cross coupling reaction.
