Bioinspired Activation of Oxygen with Pyrazole-Supported Dinuclear Copper Complexes

by Kristian Erwin Dalle
Doctoral thesis
Date of Examination:2014-10-22
Date of issue:2016-10-10
Advisor:Prof. Dr. Franc Meyer
Referee:Prof. Dr. Franc Meyer
Referee:Prof. Dr. Ulf Diederichsen
Persistent Address: http://dx.doi.org/10.53846/goediss-5887

 

 

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Abstract

English

A series of compartmental pyrazole-bridging ligands were successfully used to gain insights into copper-mediated dioxygen activation chemistry, and thus expand on the proven potential of these organic scaffolds for emulating features of dinuclear metallobiosites. Several systems were investigated in detail, leading to identification of a novel type of peroxo-dicopper(II) adduct. Crystallographic structural determination revealed an unprecedented cis-μ-1,2-peroxide binding mode of the dioxygen-derived ligand. This in turn results in properties consistent with a computationally proposed enzymatic mechanism for dioxygen activation, and allows for binding of alkali metal cations in both solution and the solid state.
Keywords: Dinuclear Copper, cis-Peroxo, Pyrazole, Oxygen Activation
 
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