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Psychopharmakotherapie in der stationären Medikamentenentzugsbehandlung - eine retrospektive Untersuchung der psychiatrischen Behandlungspraxis

dc.contributor.advisorWedekind, Dirk PD Dr.
dc.contributor.authorGiller, Teresa
dc.date.accessioned2016-11-10T10:08:23Z
dc.date.available2016-11-22T23:50:05Z
dc.date.issued2016-11-10
dc.identifier.urihttp://hdl.handle.net/11858/00-1735-0000-002B-7C9E-1
dc.identifier.urihttp://dx.doi.org/10.53846/goediss-5936
dc.identifier.urihttp://dx.doi.org/10.53846/goediss-5936
dc.language.isodeude
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.ddc610de
dc.titlePsychopharmakotherapie in der stationären Medikamentenentzugsbehandlung - eine retrospektive Untersuchung der psychiatrischen Behandlungspraxisde
dc.typedoctoralThesisde
dc.title.translatedPsychopharmacotherapy in the withdrawal treatment of inpatients with substance use disorderde
dc.contributor.refereeAlt-Epping, Bernd Prof. Dr.
dc.date.examination2016-11-15
dc.description.abstractengDespite the high clinical relevance, established guidelines for benzodiazepine-, and in particular opioid addiction are still scarce. In a retrospective design, treatment variables of inpatients with benzodiazepine- and opioid-addiction or abuse were recorded according to patients´ charts. Groups comprising patients with benzodiazepine/non-benzodiazepine abuse/addiction, opioid- and non-opioid analgetic abuse/addiction were established. 92% of all patients actually received additional pharmacologic treatment. Before all, antidepressants were prescribed (76%), but also mood-stabilizers/anticonvulsants (27%), and neuroleptic drugs (11%). Antidepressant treatment was tricyclic/tetracyclic treatment almost exclusively. Anticonvulsants, in most cases carbamazepine, was mostly prescribed for patients with combined drug use or high-dose benzodiazepine addiction, who were significantly more often treated with anticonvulsants compared to low-dose addicted subjects. Despite a negative recommendation according to AWMF-guidelines for medication addiction, low potential neuroleptic drugs were used frequently in all patient groups. 80% of included subjects had at least one comorbid psychiatric condition, before all depressive disorder, anxiety disorders, PTSD, and other adjustment disorders. 67% of patients described traumatic life-events. These were significantly more often found in high-dose compared to low dose benzodiazepine addicted patients.de
dc.contributor.coRefereeMeyer, Thomas Prof. Dr.
dc.subject.gerBenzodiazepinde
dc.subject.gerOpioidanalgetikade
dc.subject.gerNichtopioidanalgetikade
dc.subject.gerPsychopharmakotherapiede
dc.subject.gerstationärede
dc.subject.gerMedikamentenentzugsbehandlungde
dc.subject.gerEntzugde
dc.subject.gerEntzugsbehandlungde
dc.subject.engsubstancede
dc.subject.engopioidde
dc.subject.engaddictionde
dc.subject.engbenzodiazepinede
dc.subject.engnon-benzodiazepinede
dc.subject.engabusede
dc.subject.engnon-opioidde
dc.subject.engwithdrawalde
dc.subject.engpsychopharmacotherapyde
dc.identifier.urnurn:nbn:de:gbv:7-11858/00-1735-0000-002B-7C9E-1-5
dc.affiliation.instituteMedizinische Fakultätde
dc.subject.gokfullMedizin (PPN619874732)de
dc.description.embargoed2016-11-22
dc.identifier.ppn872311821


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