Angiopoietin-2 — ein neuer Biomarker bei Patienten mit akuter Lungenembolie
Angiopoietin-2 — a novel biomarker in patients with pulmonary embolism
von Caroline Niemann
Datum der mündl. Prüfung:2016-12-08
Erschienen:2016-11-28
Betreuer:Mareike Katharina Lankeit
Gutachter:Mareike Katharina Lankeit
Gutachter:Prof. Dr. Daniel Patschan
Dateien
Name:CN_DISS_SUB2.pdf
Size:1.90Mb
Format:PDF
Description:Dissertation
Zusammenfassung
Englisch
Angiopoietin-2 (Ang-2), an antagonist ligand of the endothelial-specific Tie2 receptor, inhibits the stabilizing influence of the Tie2 activator Ang-1, thereby promoting vascular remodeling. Elevated levels of Ang-2 are associated with impaired hemodynamic parameters and poor prognosis in patients with idiopathic pulmonary hypertension. This thesis aimed to investigate the prognostic value of Ang-2 in patients with acute pulmonary embolism (PE).
Keywords: pulmonary embolism; Angiopoietin-2; CTEPH
Schlagwörter: Lungenembolie; Angiopoietin-2; CTEPH