Angiopoietin-2 — ein neuer Biomarker bei Patienten mit akuter Lungenembolie
de
dc.type
doctoralThesis
de
dc.title.translated
Angiopoietin-2 — a novel biomarker in patients with pulmonary embolism
de
dc.contributor.referee
Lankeit, Mareike Katharina
dc.date.examination
2016-12-08
dc.description.abstracteng
Angiopoietin-2 (Ang-2), an antagonist ligand of the endothelial-specific Tie2 receptor, inhibits the stabilizing influence of the Tie2 activator Ang-1, thereby promoting vascular remodeling. Elevated levels of Ang-2 are associated with impaired hemodynamic parameters and poor prognosis in patients with idiopathic pulmonary hypertension. This thesis aimed to investigate the prognostic value of Ang-2 in patients with acute pulmonary embolism (PE).