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dc.contributor.advisor Maier, Lars Prof. Dr.
dc.contributor.author Neuhaus, Victor
dc.date.accessioned 2016-12-20T09:42:38Z
dc.date.available 2017-12-27T23:50:04Z
dc.date.issued 2016-12-20
dc.identifier.uri http://hdl.handle.net/11858/00-1735-0000-002B-7CEA-8
dc.language.iso deu de
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.ddc 610 de
dc.title Einfluss der Ca2+/Calmodulin-abhängigen Proteinkinase II delta auf den L-Typ Ca2+-Strom -Untersuchungen anhand eines genetischen Knock-outs im Mausmodell de
dc.type doctoralThesis de
dc.title.translated Influence of ca2+/calmodulin-dependent kinase II delta on l-type ca2+-current - investigations using a knockout model in mice de
dc.contributor.referee Schwappach-Pignataro, Blanche Prof. Dr.
dc.date.examination 2016-12-20
dc.description.abstracteng Ca2+/calmodulin-dependent kinase II delta plays an important role in heart failure as activity and expression of the kinase are higher in myocytes of failing hearts. In this dissertation transverse aortic constriction led to cardiac hypertrophy and increase of l-type ca2+-current in murine myocytes. Inhibition of ca2+/calmodulin-dependent kinase II delta using autocamtide-2-related inhibitory peptide and genetic knockout normalized l-type ca2+-current. de
dc.contributor.coReferee Oppermann, Martin Prof. Dr.
dc.subject.eng ca2+/calmodulin-dependent kinase II delta de
dc.identifier.urn urn:nbn:de:gbv:7-11858/00-1735-0000-002B-7CEA-8-2
dc.affiliation.institute Medizinische Fakultät de
dc.subject.gokfull GOK-MEDIZIN de
dc.description.embargoed 2017-12-27
dc.identifier.ppn 875215149

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